Evodiamine Stabilizes Topoisomerase I-DNA Cleavable Complex to Inhibit Topoisomerase I Activity

Evodiamine (EVO), an alkaloidal compound isolated from Evodia rutaecarpa (Juss.), has been reported to affect many physiological functions. Topoisomerase inhibitors have been developed in a variety of clinical applications. In the present study, we report the topoisomerase I (TopI) inhibitory activi...

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Detalles Bibliográficos
Autores principales: Chan, Agnes L.-F., Chang, Wen-Shin, Chen, Li-Min, Lee, Chi-Ming, Chen, Chiao-En, Lin, Chun-Mao, Hwang, Jau-Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254212/
https://www.ncbi.nlm.nih.gov/pubmed/19384267
http://dx.doi.org/10.3390/molecules14041342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254212/
https://www.ncbi.nlm.nih.gov/pubmed/19384267
http://dx.doi.org/10.3390/molecules14041342

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