Cargando…

Evodiamine Stabilizes Topoisomerase I-DNA Cleavable Complex to Inhibit Topoisomerase I Activity

Evodiamine (EVO), an alkaloidal compound isolated from Evodia rutaecarpa (Juss.), has been reported to affect many physiological functions. Topoisomerase inhibitors have been developed in a variety of clinical applications. In the present study, we report the topoisomerase I (TopI) inhibitory activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Agnes L.-F., Chang, Wen-Shin, Chen, Li-Min, Lee, Chi-Ming, Chen, Chiao-En, Lin, Chun-Mao, Hwang, Jau-Lang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254212/ https://www.ncbi.nlm.nih.gov/pubmed/19384267 http://dx.doi.org/10.3390/molecules14041342

Ejemplares similares

Menogaril, an Anthracycline Derivative, Inhibits DNA Topoisomerase II by Stabilizing Cleavable Complexes
por: Ono, Katsuhiro, et al.
Publicado: (1992)

Immobilizing topoisomerase I on a surface plasmon resonance biosensor chip to screen for inhibitors
por: Tsai, Hsiang-Ping, et al.
Publicado: (2010)

Immunodetection of human topoisomerase I-DNA covalent complexes
por: Patel, Anand G., et al.
Publicado: (2016)

Response to ICRF-159 in cell lines resistant to cleavable complex-forming topoisomerase II inhibitors.
por: Davies, S. L., et al.
Publicado: (1997)

The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA–topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts
por: Dexheimer, Thomas S., et al.
Publicado: (2008)

Bacterial topoisomerase I and topoisomerase III relax supercoiled DNA via distinct pathways
por: Terekhova, Ksenia, et al.
Publicado: (2012)

Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer
por: Lee, Yu-Chieh, et al.
Publicado: (2015)

Structural studies of type I topoisomerases
por: Baker, Nicole M., et al.
Publicado: (2009)

Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation
por: González-Ruiz, Víctor, et al.
Publicado: (2021)

Copper Complexes as Anticancer Agents Targeting Topoisomerases I and II
por: Molinaro, Caroline, et al.
Publicado: (2020)

Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
por: Xu, Huanli, et al.
Publicado: (2016)

Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA
por: Rosa, Ilaria Dalla, et al.
Publicado: (2009)

Small DNA circles as bacterial topoisomerase I inhibitors
por: Li, Dawei, et al.
Publicado: (2019)

Low-level resistance to camptothecin in a human small-cell lung cancer cell line without reduction in DNA topoisomerase I or drug-induced cleavable complex formation.
por: Sorensen, M., et al.
Publicado: (1998)

Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I
por: Das, Benu Brata, et al.
Publicado: (2006)

Topoisomerase I in Human Disease Pathogenesis and Treatments
por: Li, Min, et al.
Publicado: (2016)

CK2-Mediated Hyperphosphorylation of Topoisomerase I Targets Serine 506, Enhances Topoisomerase I–DNA Binding, and Increases Cellular Camptothecin Sensitivity
por: Bandyopadhyay, Keya, et al.
Publicado: (2012)

Association of Anti–Topoisomerase I Antibodies of the IgM Isotype With Disease Progression in Anti–Topoisomerase I–Positive Systemic Sclerosis
por: Boonstra, Maaike, et al.
Publicado: (2020)

Novel bivalent securinine mimetics as topoisomerase I inhibitors
por: Hou, Wen, et al.
Publicado: (2017)

On the viability of Escherichia coli cells lacking DNA topoisomerase I
por: Stockum, Anna, et al.
Publicado: (2012)

Topoisomerase I prevents transcription-replication conflicts at transcription termination sites
por: Liu, Yaqun, et al.
Publicado: (2020)

Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activity
por: Huang, Yahui, et al.
Publicado: (2020)

Enhanced Topoisomerase I Activity and Increased Topoisomerase IIα Content in Cisplatin‐resistant Cancer Cell Lines
por: Minagawa, Yukihisa, et al.
Publicado: (1997)

C-terminal lysine repeats in Streptomyces topoisomerase I stabilize the enzyme–DNA complex and confer high enzyme processivity
por: Strzałka, Agnieszka, et al.
Publicado: (2017)

New Topoisomerase I mutations are associated with resistance to camptothecin
por: Gongora, Céline, et al.
Publicado: (2011)

Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I
por: Sobek, Stefan, et al.
Publicado: (2013)

Autoregulation of topoisomerase I expression by supercoiling sensitive transcription
por: Ahmed, Wareed, et al.
Publicado: (2016)

Bulge oligonucleotide as an inhibitory agent of bacterial topoisomerase I
por: Yang, Zhaoqi, et al.
Publicado: (2017)

‘LeishMan’ topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani
por: Ganguly, Agneyo, et al.
Publicado: (2006)

DNA topoisomerase I and II expression in drug resistantgerm cell tumours
por: Berney, D M, et al.
Publicado: (2002)

Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase
por: Ahmed, Wareed, et al.
Publicado: (2017)

Why Should DNA Topoisomerase I Have a Scaffold Activity?
por: Di Felice, Francesca, et al.
Publicado: (2021)

Two type I topoisomerases maintain DNA topology in human mitochondria
por: Menger, Katja E, et al.
Publicado: (2022)

Structural and Dynamical Effects Induced by the Anticancer Drug Topotecan on the Human Topoisomerase I – DNA Complex
por: Mancini, Giordano, et al.
Publicado: (2010)

Phase I study of sequentially administered topoisomerase I inhibitor (irinotecan) and topoisomerase II inhibitor (etoposide) for metastatic non-small-cell lung cancer.
por: Ando, M., et al.
Publicado: (1997)

Expanding the type IIB DNA topoisomerase family: identification of new topoisomerase and topoisomerase-like proteins in mobile genetic elements
por: Takahashi, Diane T, et al.
Publicado: (2019)

The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I
por: Gentry, Amanda C., et al.
Publicado: (2011)

Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes
por: Regairaz, Marie, et al.
Publicado: (2011)

Bacterial topoisomerase I as a target for discovery of antibacterial compounds
por: Tse-Dinh, Yuk-Ching
Publicado: (2009)

A functional type I topoisomerase from Pseudomonas aeruginosa
por: Jain, Teesta, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_o1okroe2v5a4nu1c85bnokd99r