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1424. Examining the Relationship Between Vancomycin Area Under the Concentration–Time Curve and Serum Trough Levels in Adults with Presumed or Documented Staphylococcal Infections

BACKGROUND: Recent studies evaluating area under the concentration–time curve (AUC)-guided vancomycin dosing have reported reduced drug exposure and nephrotoxicity as compared with traditional trough-guided (target 15–20 mg/L) dosing for invasive infections, but studies exploring the relationship be...

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Detalles Bibliográficos
Autores principales: Clark, Laura, Skrupky, Lee P, Servais, Ryan, Brummitt, Charles F, Dilworth, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254292/
http://dx.doi.org/10.1093/ofid/ofy210.1255