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1414. Inoculum Effect of Piperacillin/Tazobactam Concentration on Emergence of Resistance in Klebsiella aerogenes

BACKGROUND: Piperacillin/tazobactam (PTZ) is a carbapenem-sparing option for AmpC-repressed organisms. Current strategies of dosing PTZ focus on prolonging fT > minimum inhibitory concentration (MIC), lowering C:MIC ratios. The objective of this study was to determine the effect of physiologic PT...

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Detalles Bibliográficos
Autores principales: Custodio, Marco, Anderson, Beverly, Sanchez, Daniel, Ryan, Keenan, Walraven, Carla, Mercier, Renee-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254299/
http://dx.doi.org/10.1093/ofid/ofy210.1245