Depletion of plasma membrane–associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg(2+), spermine, and pH

Transient receptor potential cation channel subfamily M member 7 (TRPM7) is an ion channel/protein kinase belonging to the TRP melastatin and eEF2 kinase families. Under physiological conditions, most native TRPM7 channels are inhibited by cytoplasmic Mg(2+), protons, and polyamines. Currents throug...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhelay, Tetyana, Wieczerzak, Krystyna B., Beesetty, Pavani, Alter, Gerald M., Matsushita, Masayuki, Kozak, J. Ashot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254349/
https://www.ncbi.nlm.nih.gov/pubmed/30305398
http://dx.doi.org/10.1074/jbc.RA118.004066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254349/
https://www.ncbi.nlm.nih.gov/pubmed/30305398
http://dx.doi.org/10.1074/jbc.RA118.004066

Ejemplares similares