A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins

The retroviral restriction factor tripartite motif–containing 5α (Trim5α) acts during the early postentry stages of the retroviral life cycle to block infection by a broad range of retroviruses, disrupting reverse transcription and integration. The mechanism of this restriction is poorly understood,...

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Detalles Bibliográficos
Autores principales: Keown, Jeremy R., Black, Moyra M., Ferron, Aaron, Yap, Melvyn, Barnett, Michael J., Pearce, F. Grant, Stoye, Jonathan P., Goldstone, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254359/
https://www.ncbi.nlm.nih.gov/pubmed/30282803
http://dx.doi.org/10.1074/jbc.RA118.004202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254359/
https://www.ncbi.nlm.nih.gov/pubmed/30282803
http://dx.doi.org/10.1074/jbc.RA118.004202

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