698. Nacubactam Inhibits Class A β-lactamases

BACKGROUND: Nacubactam, formerly RG6080 and OP0595 (Figure 1A), is a bridged diazabicyclooctane (DBO) that inactivates class A and class C β-lactamases. Unlike avibactam, the DBO that is approved for use in combination with ceftazidime, nacubactam also inhibits penicillin binding proteins (i.e., PBP...

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Detalles Bibliográficos
Autores principales: Barnes, Melissa D, Good, Caryn E, Bajaksouzian, Saralee, Taracila, Magdalena A, Duin, David Van, Kreiswirth, Barry N, Jacobs, Michael R, Papp-Wallace, Krisztina M, Bonomo, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254451/
http://dx.doi.org/10.1093/ofid/ofy210.705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254451/
http://dx.doi.org/10.1093/ofid/ofy210.705

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