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Sepsis Induces a Long-Lasting State of Trained Immunity in Bone Marrow Monocytes
Innate immune memory describes the functional reprogramming of innate immune cells after pathogen contact, leading to either a boosted (trained immunity) or a diminished (immune tolerance) response to a secondary stimulus. Immune tolerance or “sepsis-induced immunosuppression” is a typical hallmark...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254543/ https://www.ncbi.nlm.nih.gov/pubmed/30510555 http://dx.doi.org/10.3389/fimmu.2018.02685 |