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The possible effect of SCN1A and SCN2A genetic variants on carbamazepine response among Khyber Pakhtunkhwa epileptic patients, Pakistan

PURPOSE: SCN1A (3184 A>G) and SCN2A (56G>A) gene encodes α subunit of the neuronal voltage-gated sodium channel, which is a target for carbamazepine (CBZ). Recent studies have demonstrated that polymorphism of SCN1A (3184 A>G) and SCN2A (56G>A) was associated with use of CBZ. However, it...

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Detalles Bibliográficos
Autores principales: Nazish, Haleema Rehana, Ali, Niaz, Ullah, Shakir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254658/
https://www.ncbi.nlm.nih.gov/pubmed/30538486
http://dx.doi.org/10.2147/TCRM.S180827