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Attaining threshold antibody cytotoxicity for selective tumor cell destruction: an opinion article
We propose a novel immunotherapeutic paradigm that justifies application of several antibodies to various membrane-associated antigens to achieve a critical threshold density of immune complexes on the surface of cancer cells sufficient for triggering downstream cytolytic pathways. Indeed, some canc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254663/ https://www.ncbi.nlm.nih.gov/pubmed/30515270 http://dx.doi.org/10.18632/oncotarget.26271 |