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Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumors

CGP results from >60,000 cases were screened to identify NTRK fusion events from cases of neuroendocrine tumors. 2417 NET patients from diverse anatomic sites were identified. From this dataset, six cases harbored NTRK fusions which included intra- and inter-chromosomal translocations. A NTRK fus...

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Detalles Bibliográficos
Autores principales: Sigal, Darren S., Bhangoo, Munveer S., Hermel, Jonathan A., Pavlick, Dean C., Frampton, Garrett, Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254675/
https://www.ncbi.nlm.nih.gov/pubmed/30533196
http://dx.doi.org/10.18632/oncotarget.26260