Generation of 500-Member Library of 10-Alkyl-2-R(1),3-R(2)-4,10-DihydrobenzoDihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones

Representative benzimidazopyrimidinones were previously reported to be intercalating antitumor agents. In this work, we used 2-substituted 4,10-dihydrobenzo Dihydrobenzo[4,5]imidazo[1,2-a]pyriminin-4-ones for their diversification by regioselective alkylation. Under the conditions established, the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Sirko, Svetlana M., Gorobets, Nikolay Yu., Musatov, Vladimir I., Desenko, Sergey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254725/
https://www.ncbi.nlm.nih.gov/pubmed/20032888
http://dx.doi.org/10.3390/molecules14125223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254725/
https://www.ncbi.nlm.nih.gov/pubmed/20032888
http://dx.doi.org/10.3390/molecules14125223

Ejemplares similares