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2307. Use of Whole-Genome Sequencing to Determine Adhesin and Biofilm-Associated Gene Profiles Among Pediatric Staphylococcus aureus Device-Related Infection Isolates Compared With Skin and Soft-Tissue Infection Isolates

BACKGROUND: Adhesins or microbial surface component recognizing adhesive matrix molecules (MSCRAMMs) and the ica locus help mediate S. aureus adherence to host tissue and biofilm formation and are thought to play important roles in the pathogenesis of device related infections (DRIs). We hypothesize...

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Detalles Bibliográficos
Autores principales: Foster, Catherine, Kok, Melissa, Flores, Anthony, Luna, Ruth Ann, Kaplan, Sheldon L, Hulten, Kristina G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254756/
http://dx.doi.org/10.1093/ofid/ofy210.1960