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Recent Advances in the Discovery of Haem-Targeting Drugs for Malaria and Schistosomiasis

Haem is believed to be the target of some of the historically most important antimalarial drugs, most notably chloroquine. This target is almost ideal as haem is host-derived and the process targeted, haemozoin formation, is a physico-chemical process with no equivalent in the host. The result is th...

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Detalles Bibliográficos
Autores principales: de Villiers, Katherine A., Egan, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254801/
https://www.ncbi.nlm.nih.gov/pubmed/19701131
http://dx.doi.org/10.3390/molecules14082868