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Solid-Phase Synthesis of Optically Active Substituted 2-Aminofuranones Using an Activated Carbonate Linker

An efficient three-step solid-phase synthesis of diverse 3,5-disubstituted-2-aminofuranones has been developed. α-Hydroxy acids loaded on a nitrophenyl carbonate derivative of Wang resin are used as acylating agents for the C-acylation of active methylene compounds and the resulting intermediates pr...

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Detalles Bibliográficos
Autores principales: Matiadis, Dimitris, Prousis, Kyriakos C., Igglessi-Markopoulou, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254804/
https://www.ncbi.nlm.nih.gov/pubmed/19924038
http://dx.doi.org/10.3390/molecules14103914