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Paclitaxel-resistant gastric cancer MGC-803 cells promote epithelial-to-mesenchymal transition and chemoresistance in paclitaxel-sensitive cells via exosomal delivery of miR-155-5p

Paclitaxel is a first-line chemotherapeutic agent for gastric cancer; however, resistance limits its effectiveness. Investigation into the underlying mechanisms of paclitaxel resistance is urgently required. In the present study, a paclitaxel-resistant gastric cancer cell line (MGC-803R) was generat...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Qiu, Rong, Yu, Shaorong, Xu, Xiaoyue, Li, Gang, Gu, Rongmin, Tan, Caihong, Zhu, Wei, Shen, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254863/
https://www.ncbi.nlm.nih.gov/pubmed/30365045
http://dx.doi.org/10.3892/ijo.2018.4601