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New Synthesis and Antiparasitic Activity of Model 5-Aryl-1-methyl-4-nitroimidazoles

A number of 5-aryl-1-methyl-4-nitroimidazoles 5a-f have been synthesized in good yields by the Suzuki coupling reaction between 5-chloro-1-methyl-4-nitroimidazole (3) and arylboronic acids 4a-f, aided by dichlorobis-(triphenylphosphine)palladium(II), K(2)CO(3,) and tetrabutylammonium bromide in wate...

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Detalles Bibliográficos
Autores principales: Saadeh, Haythem A., Mosleh, Ibrahim M., El-Abadelah, Mustafa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254920/
https://www.ncbi.nlm.nih.gov/pubmed/19701122
http://dx.doi.org/10.3390/molecules14082758