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HIF-1α contributes to tube malformation of human lymphatic endothelial cells by upregulating VEGFR-3
Hypoxia-inducible factor-1α (HIF-1α) is upregulated in various tumors and associated with lymphangiogenesis and angiogenesis during tumor development and metastasis. However, the role of HIF-1α in cystic lymphatic malformations (cLM) remains unclear. In the present study, expression of HIF-1α and va...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254933/ https://www.ncbi.nlm.nih.gov/pubmed/30431105 http://dx.doi.org/10.3892/ijo.2018.4623 |