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Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability
BACKGROUND: As one of the most invasive cutaneous carcinomas among all types of skin cancer, malignant melanoma remains a severe challenge in oncology and plastic surgery. Selective small-molecule inhibitors of V600E-mutant B-Raf (vemurafenib, for instance) have demonstrated satisfactory therapeutic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255049/ https://www.ncbi.nlm.nih.gov/pubmed/30538498 http://dx.doi.org/10.2147/OTT.S183311 |