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Synthesis of Lipoamino Acids and Their Activity against Cerebral Ischemic Injury

A series of lipoamino acids were synthesized and their neuroprotective effect against brain ischemia induced by oxygen-glucose deprivation (OGD) on rat cerebral slices was evaluated. Among these compounds, N-stearoyl-l-tyrosine (4), N-stearoyl-l-serine (5) and N-stearoyl-L-threonine (6) exhibited go...

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Detalles Bibliográficos
Autores principales: Yao, Li-Yun, Lin, Qi, Niu, Yin-Yao, Deng, Ke-Min, Zhang, Jian-Hua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255101/
https://www.ncbi.nlm.nih.gov/pubmed/19924046
http://dx.doi.org/10.3390/molecules14104051