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A General Synthesis of C8-Arylpurine Phosphoramidites

A general scheme for the synthesis of C8-arylpurine phosphoramidites has been developed. C8-Arylation of C8-bromo-2′-deoxyguanosine is the key step and has been achieved through the use of a Suzuki coupling. Since the coupling reaction is conducted under aqueous conditions, it is unnecessary to prot...

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Detalles Bibliográficos
Autores principales:	Vongsutilers, Vorasit, Daft, Jonathan R., Shaughnessy, Kevin H., Gannett, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255102/ https://www.ncbi.nlm.nih.gov/pubmed/19783928 http://dx.doi.org/10.3390/molecules14093339

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