Cargando…

Fabrication and evaluation of a γ-PGA-based self-assembly transferrin receptor-targeting anticancer drug carrier

BACKGROUND: cis-Dichlorodiamineplatinum (CDDP) was one of the most common used drugs in clinic for cancer treatment. However, CDDP caused a variety of side effects. The abundant carboxyl groups on the surface of poly glutamic acid (PGA) could be modified with various kinds of targeted ligands. PGA d...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Li, Zhu, Xiaoyu, Wu, Shijia, Chen, Yazhou, Tan, Shiming, Liu, Yingjie, Jiang, Wenzheng, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255109/
https://www.ncbi.nlm.nih.gov/pubmed/30538465
http://dx.doi.org/10.2147/IJN.S181121