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Synthesis of Chiral 1,4-Disubstituted-1,2,3-Triazole Derivatives from Amino Acids

A versatile method for the synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives starting from easily accessible naturally occurring D-or L-amino acids as chiral synthons is described. The amino acids were converted into azido alcohols, followed by copper catalyzed [3+2] cycloaddition rea...

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Detalles Bibliográficos
Autores principales: Klein, Michael, Krainz, Karin, Redwan, Itedale Namro, Dinér, Peter, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255254/
https://www.ncbi.nlm.nih.gov/pubmed/20032880
http://dx.doi.org/10.3390/molecules14125124