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Leishmanicidal Activity of Aliphatic and Aromatic Lactones: Correlation Structure-Activity

Several aliphatic and aromatic lactones and two dimers were synthesized using the sequence: allylation - esterification - metathesis. These compounds were active in vitro against intracellular amastigotes of Leishmania panamensis. The structure-activity relationship showed the importance of the alip...

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Detalles Bibliográficos
Autores principales: Castaño, Marcela, Cardona, Wilson, Quiñones, Winston, Robledo, Sara, Echeverri, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255270/
https://www.ncbi.nlm.nih.gov/pubmed/19633618
http://dx.doi.org/10.3390/molecules14072491