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652. What Is Blood Got to Do with It? Genetic Susceptibility to Norovirus and Rotavirus Infection: Results From the SUPERNOVA Network

BACKGROUND: Histo-blood group antigens (HBGAs), whose expression is controlled in part by fucosyltransferase 2 (FUT2) and 3 (FUT3) genes, serve as receptors for norovirus and rotavirus. Individuals without functional FUT2 (nonsecretors) or FUT3 (Lewis-negative) genes may have decreased susceptibilit...

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Detalles Bibliográficos
Autores principales: Kambhampati, Anita, Atmar, Robert L, Neill, Frederick H, Rodriguez-Barradas, Maria C, Vargas, Blanca, Beenhouwer, David O, Poteshkina, Aleksandra, Marconi, Vincent C, Meagley, Kathryn L, Brown, Sheldon T, Perea, Adrienne, Browne, Hannah, Gautam, Rashi, Grytdal, Scott, Bowen, Michael D, Vinjé, Jan, Parashar, Umesh D, Hall, Aron J, Cardemil, Cristina V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255288/
http://dx.doi.org/10.1093/ofid/ofy210.659