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Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation

The condensation of chlorides of substituted pyrazinecarboxylic acids with ring-substituted anilines yielded twelve substituted pyrazinecarboxylic acid amides. The synthetic approach, analytical, and lipophilicity data of the newly synthesized compounds are presented. Two antituberculosis assays wer...

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Detalles Bibliográficos
Autores principales: Doležal, Martin, Zitko, Jan, Kešetovičová, Diana, Kuneš, Jiří, Svobodová, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255326/
https://www.ncbi.nlm.nih.gov/pubmed/19924056
http://dx.doi.org/10.3390/molecules14104180