New 1-Aryl-3-Substituted Propanol Derivatives as Antimalarial Agents

This paper describes the synthesis and in vitro antimalarial activity against a P. falciparum 3D7 strain of some new 1-aryl-3-substituted propanol derivatives. Twelve of the tested compounds showed an IC(50) lower than 1 µM. These compounds were also tested for cytotoxicity in murine J774 macrophage...

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Detalles Bibliográficos
Autores principales: Pérez-Silanes, Silvia, Berrade, Luis, García–Sánchez, Rory N., Mendoza, Adela, Galiano, Silvia, Pérez-Solórzano, Berta Martín, Nogal-Ruiz, Juan J., Martínez-Fernández, Antonio R., Aldana, Ignacio, Monge, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255377/
https://www.ncbi.nlm.nih.gov/pubmed/19924051
http://dx.doi.org/10.3390/molecules14104120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255377/
https://www.ncbi.nlm.nih.gov/pubmed/19924051
http://dx.doi.org/10.3390/molecules14104120

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