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A New Synthetic Compound, 2-OH, Enhances Interleukin-2 and Interferon-γ Gene Expression in Human Peripheral Blood Mononuclear Cells

A new synthetic compound, 6-hydroxy-2-tosylisoquinolin-1(2H)-one (2-OH), was selected for immunopharmacological activity tests. The effects of 2-OH on human peripheral blood mononuclear cell (PBMC) proliferation were determined by tritiated thymidine uptake. Compared to phytohemagglutinin (PHA; 5 μg...

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Detalles Bibliográficos
Autores principales: Chou, Shiu-Huey, Chou, Shang-Shing P., Liew, Yih-Fong, Leu, Jyh-Yih, Wang, Su-Jane, Huang, Rwei-Fen S., Tzeng, Woan-Fang, Kuo, Yuh-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255383/
https://www.ncbi.nlm.nih.gov/pubmed/19633608
http://dx.doi.org/10.3390/molecules14072345