Silibinin Suppresses TNF-α-Induced MMP-9 Expression in Gastric Cancer Cells through Inhibition of the MAPK Pathway

Tumor necrosis factor (TNF)-α is one of the pro-inflammatory cytokines highly expressed in Helicobacter pylori that inhibits gastric acid secretion. In this study we determined the effect of silibinin on TNF-α-induced MMP-9 expression in gastric cancer cell lines. MMP-9 mRNA and protein expression w...

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Detalles Bibliográficos
Autores principales: Kim, Sangmin, Choi, Min Gew, Lee, Hye Sook, Lee, Se Kyung, Kim, Sung Hoon, Kim, Wan Wook, Hur, Sung Mo, Kim, Jung-Han, Choe, Jun-Ho, Nam, Seok Jin, Yang, Jung-Hyun, Kim, Sung, Lee, Jeong Eon, Kim, Jee Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255431/
https://www.ncbi.nlm.nih.gov/pubmed/19924065
http://dx.doi.org/10.3390/molecules14114300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255431/
https://www.ncbi.nlm.nih.gov/pubmed/19924065
http://dx.doi.org/10.3390/molecules14114300

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