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di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo

The P(IB) ATPase heavy metal ATPase 4 (HMA4) has a central role in the zinc homeostasis network of Arabidopsis thaliana. This membrane protein loads metal from the pericycle cells into the xylem in roots, thereby allowing root to shoot metal translocation. Moreover, HMA4 is key for zinc hyperaccumul...

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Detalles Bibliográficos
Autores principales: Lekeux, Gilles, Laurent, Clémentine, Joris, Marine, Jadoul, Alice, Jiang, Dan, Bosman, Bernard, Carnol, Monique, Motte, Patrick, Xiao, Zhiguang, Galleni, Moreno, Hanikenne, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255694/
https://www.ncbi.nlm.nih.gov/pubmed/30137564
http://dx.doi.org/10.1093/jxb/ery311