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Structural basis of RIP2 activation and signaling

Signals arising from bacterial infections are detected by pathogen recognition receptors (PRRs) and are transduced by specialized adapter proteins in mammalian cells. The Receptor-interacting-serine/threonine-protein kinase 2 (RIPK2 or RIP2) is such an adapter protein that is critical for signal pro...

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Detalles Bibliográficos
Autores principales: Gong, Qin, Long, Ziqi, Zhong, Franklin L., Teo, Daniel Eng Thiam, Jin, Yibo, Yin, Zhan, Boo, Zhao Zhi, Zhang, Yaming, Zhang, Jiawen, Yang, Renliang, Bhushan, Shashi, Reversade, Bruno, Li, Zongli, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255760/
https://www.ncbi.nlm.nih.gov/pubmed/30478312
http://dx.doi.org/10.1038/s41467-018-07447-9