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A novel fluorescein-bisphosphonate based diagnostic tool for the detection of hydroxyapatite in both cell and tissue models

A rapid and efficient method for the detection of hydroxyapatite (HAP) has been developed which shows superiority to existing well-established methods. This fluorescein-bisphosphonate probe is highly selective for HAP over other calcium minerals and is capable of detecting lower levels of calcificat...

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Detalles Bibliográficos
Autores principales: Sim, Alisia M., Rashdan, Nabil A., Cui, Lin, Moss, Alastair J., Nudelman, Fabio, Dweck, Marc R., MacRae, Vicky E., Hulme, Alison N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255785/
https://www.ncbi.nlm.nih.gov/pubmed/30478332
http://dx.doi.org/10.1038/s41598-018-35454-9