Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

Octahydroindolo[2,3-a]quinolizine ring system forms the basic framework comprised of more than 2000 distinct family members of natural products. Despite the potential applications of this privileged substructure in drug discovery, efficient, atom-economic and modular strategies for its assembly, is...

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Detalles Bibliográficos
Autores principales: Srinivasulu, Vunnam, Schilf, Paul, Ibrahim, Saleh, Khanfar, Monther A., Sieburth, Scott McN, Omar, Hany, Sebastian, Anusha, AlQawasmeh, Raed A., O’Connor, Matthew John, Al-Tel, Taleb H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255838/
https://www.ncbi.nlm.nih.gov/pubmed/30478283
http://dx.doi.org/10.1038/s41467-018-07521-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255838/
https://www.ncbi.nlm.nih.gov/pubmed/30478283
http://dx.doi.org/10.1038/s41467-018-07521-2

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