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Using Frameshift Peptide Arrays for Cancer Neo-Antigens Screening

It has been demonstrated that DNA mutations generating neo-antigens are important for an effective immune response to tumors as evident from recent clinical studies of immune checkpoint inhibitors (ICIs). Further, it was shown that frameshift peptides (FSP) generated in tumors from insertions and de...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Shen, Luhui, Johnston, Stephen Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255861/
https://www.ncbi.nlm.nih.gov/pubmed/30478295
http://dx.doi.org/10.1038/s41598-018-35673-0