Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-inflammation in a 3xTg-AD mouse model

Alzheimer’s disease (AD) is the most common form of dementia and is characterized by an imbalance between the production and clearance of amyloid-beta (Aβ) and tau proteins. Although vaccination against Aβ peptide results in a dramatic reduction in Aβ pathology in experimental mouse models, the init...

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Detalles Bibliográficos
Autores principales: Baek, Hyunjung, Lee, Chan-ju, Choi, Da Bin, Kim, Nam-sik, Kim, Yong-Suk, Ye, Young Jun, Kim, Youn-Sub, Kim, Jin Su, Shim, Insop, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255868/
https://www.ncbi.nlm.nih.gov/pubmed/30478329
http://dx.doi.org/10.1038/s41598-018-35030-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255868/
https://www.ncbi.nlm.nih.gov/pubmed/30478329
http://dx.doi.org/10.1038/s41598-018-35030-1

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