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Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections

Sirtuin 5 (SIRT5) is a member of the family of NAD(+)-dependent lysine/histone deacetylases. SIRT5 resides mainly in the mitochondria where it catalyzes deacetylation, demalonylation, desuccinylation, and deglutarylation of lysine to regulate metabolic and oxidative stress response pathways. Pharmac...

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Detalles Bibliográficos
Autores principales: Heinonen, Tytti, Ciarlo, Eleonora, Théroude, Charlotte, Pelekanou, Aimilia, Herderschee, Jacobus, Le Roy, Didier, Roger, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255879/
https://www.ncbi.nlm.nih.gov/pubmed/30515162
http://dx.doi.org/10.3389/fimmu.2018.02675