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Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections
Sirtuin 5 (SIRT5) is a member of the family of NAD(+)-dependent lysine/histone deacetylases. SIRT5 resides mainly in the mitochondria where it catalyzes deacetylation, demalonylation, desuccinylation, and deglutarylation of lysine to regulate metabolic and oxidative stress response pathways. Pharmac...
Autores principales: | Heinonen, Tytti, Ciarlo, Eleonora, Théroude, Charlotte, Pelekanou, Aimilia, Herderschee, Jacobus, Le Roy, Didier, Roger, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255879/ https://www.ncbi.nlm.nih.gov/pubmed/30515162 http://dx.doi.org/10.3389/fimmu.2018.02675 |
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