Total flavonoids from Semen Cuscutae target MMP9 and promote invasion of EVT cells via Notch/AKT/MAPK signaling pathways

Miscarriage is a common condition during pregnancy and its mechanisms remain largely unknown. Extravillous trophoblast (EVT) cell invasion is required to maintain normal pregnancy and its malfunction has been proposed as a major cause for miscarriage. Homeostasis of matrix metalloproteinase 9 (MMP9)...

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Detalles Bibliográficos
Autores principales: Gao, Feixia, Zhou, Chun, Qiu, Weiyu, Wu, Haiwang, Li, Jing, Peng, Jinting, Qiu, Min, Liang, Chun, Gao, Jie, Luo, Songping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255888/
https://www.ncbi.nlm.nih.gov/pubmed/30478366
http://dx.doi.org/10.1038/s41598-018-35732-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255888/
https://www.ncbi.nlm.nih.gov/pubmed/30478366
http://dx.doi.org/10.1038/s41598-018-35732-6

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