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Total flavonoids from Semen Cuscutae target MMP9 and promote invasion of EVT cells via Notch/AKT/MAPK signaling pathways
Miscarriage is a common condition during pregnancy and its mechanisms remain largely unknown. Extravillous trophoblast (EVT) cell invasion is required to maintain normal pregnancy and its malfunction has been proposed as a major cause for miscarriage. Homeostasis of matrix metalloproteinase 9 (MMP9)...
Autores principales: | Gao, Feixia, Zhou, Chun, Qiu, Weiyu, Wu, Haiwang, Li, Jing, Peng, Jinting, Qiu, Min, Liang, Chun, Gao, Jie, Luo, Songping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255888/ https://www.ncbi.nlm.nih.gov/pubmed/30478366 http://dx.doi.org/10.1038/s41598-018-35732-6 |
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