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Iron removal enhances vitamin C-induced apoptosis and growth inhibition of K-562 leukemic cells

Although vitamin C (VC) has recently garnered interest as an alternative cancer therapy, its clinical effects remain controversial. It was recently reported using in vitro prostate cancer cell lines that excess extracellular iron (EEI) diminishes anti-cancer effects of VC, promoting the decompositio...

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Detalles Bibliográficos
Autores principales: Tsuma-Kaneko, Mitsuyo, Sawanobori, Masakazu, Kawakami, Shohei, Uno, Tomoko, Nakamura, Yoshihiko, Onizuka, Makoto, Ando, Kiyoshi, Kawada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255900/
https://www.ncbi.nlm.nih.gov/pubmed/30478296
http://dx.doi.org/10.1038/s41598-018-35730-8