CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer

High grade serous ovarian carcinoma (HGSOC) is often diagnosed at an advanced stage. Chromobox 2 (CBX2), a polycomb repressor complex subunit, plays an oncogenic role in other cancers, but little is known about its role in HGSOC. We hypothesize that CBX2 upregulation promotes HGSOC via induction of...

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Detalles Bibliográficos
Autores principales: Wheeler, Lindsay J., Watson, Zachary L., Qamar, Lubna, Yamamoto, Tomomi M., Post, Miriam D., Berning, Amber A., Spillman, Monique A., Behbakht, Kian, Bitler, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255906/
https://www.ncbi.nlm.nih.gov/pubmed/30478317
http://dx.doi.org/10.1038/s41389-018-0103-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255906/
https://www.ncbi.nlm.nih.gov/pubmed/30478317
http://dx.doi.org/10.1038/s41389-018-0103-1

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