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CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer
High grade serous ovarian carcinoma (HGSOC) is often diagnosed at an advanced stage. Chromobox 2 (CBX2), a polycomb repressor complex subunit, plays an oncogenic role in other cancers, but little is known about its role in HGSOC. We hypothesize that CBX2 upregulation promotes HGSOC via induction of...
Autores principales: | Wheeler, Lindsay J., Watson, Zachary L., Qamar, Lubna, Yamamoto, Tomomi M., Post, Miriam D., Berning, Amber A., Spillman, Monique A., Behbakht, Kian, Bitler, Benjamin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255906/ https://www.ncbi.nlm.nih.gov/pubmed/30478317 http://dx.doi.org/10.1038/s41389-018-0103-1 |
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