RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation

RANKL signaling is essential for osteoclastogenesis. Its role in osteoblastic differentiation and bone formation is unknown. Here we demonstrate that RANK is expressed at an early stage of bone marrow mesenchymal stem cells (BMSCs) during osteogenic differentiation in both mice and human and decreas...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Zhi, Xin, Wang, Jun, Su, Jiacan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255918/
https://www.ncbi.nlm.nih.gov/pubmed/30510839
http://dx.doi.org/10.1038/s41413-018-0035-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255918/
https://www.ncbi.nlm.nih.gov/pubmed/30510839
http://dx.doi.org/10.1038/s41413-018-0035-6

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