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Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells

Accumulation of damaged or misfolded proteins resulted from oxidative protein modification induces endoplasmic reticulum (ER) stress by activating the pathways of unfolded protein response. In pathologic hemolytic conditions, extracellular free hemoglobin is submitted to rapid oxidation causing heme...

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Detalles Bibliográficos
Autores principales: Gáll, Tamás, Pethő, Dávid, Nagy, Annamária, Hendrik, Zoltán, Méhes, Gábor, Potor, László, Gram, Magnus, Åkerström, Bo, Smith, Ann, Nagy, Péter, Balla, György, Balla, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255930/
https://www.ncbi.nlm.nih.gov/pubmed/30515102
http://dx.doi.org/10.3389/fphys.2018.01595