Cargando…
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells
Accumulation of damaged or misfolded proteins resulted from oxidative protein modification induces endoplasmic reticulum (ER) stress by activating the pathways of unfolded protein response. In pathologic hemolytic conditions, extracellular free hemoglobin is submitted to rapid oxidation causing heme...
Autores principales: | Gáll, Tamás, Pethő, Dávid, Nagy, Annamária, Hendrik, Zoltán, Méhes, Gábor, Potor, László, Gram, Magnus, Åkerström, Bo, Smith, Ann, Nagy, Péter, Balla, György, Balla, József |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255930/ https://www.ncbi.nlm.nih.gov/pubmed/30515102 http://dx.doi.org/10.3389/fphys.2018.01595 |
Ejemplares similares
-
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression
por: Pethő, Dávid, et al.
Publicado: (2021) -
Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress—A New Insight into the Pathophysiology of Vascular Diseases
por: Gáll, Tamás, et al.
Publicado: (2019) -
Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation
por: Pethő, Dávid, et al.
Publicado: (2021) -
Therapeutic Potential of Carbon Monoxide (CO) and Hydrogen Sulfide (H(2)S) in Hemolytic and Hemorrhagic Vascular Disorders—Interaction between the Heme Oxygenase and H(2)S-Producing Systems
por: Gáll, Tamás, et al.
Publicado: (2020) -
Overview on hydrogen sulfide-mediated suppression of vascular calcification and hemoglobin/heme-mediated vascular damage in atherosclerosis
por: Gáll, Tamás, et al.
Publicado: (2022)