Reconstitution of the Ataxia-Telangiectasia Cellular Phenotype With Lentiviral Vectors

Ataxia-telangiectasia (A-T) is a complex disease arising from mutations in the ATM gene (Ataxia-Telangiectasia Mutated), which plays crucial roles in repairing double-strand DNA breaks (DSBs). Heterogeneous immunodeficiency, extreme radiosensitivity, frequent appearance of tumors and neurological de...

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Detalles Bibliográficos
Autores principales: Carranza, Diana, Torres-Rusillo, Sara, Ceballos-Pérez, Gloria, Blanco-Jimenez, Eva, Muñoz-López, Martin, García-Pérez, José L., Molina, Ignacio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255946/
https://www.ncbi.nlm.nih.gov/pubmed/30515174
http://dx.doi.org/10.3389/fimmu.2018.02703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255946/
https://www.ncbi.nlm.nih.gov/pubmed/30515174
http://dx.doi.org/10.3389/fimmu.2018.02703

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