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Cell Death Is Counteracted by Mitophagy in HIV-Productively Infected Astrocytes but Is Promoted by Inflammasome Activation Among Non-productively Infected Cells

Despite more than 30 years of extensive research efforts, a complete understanding of the neurological consequences of HIV central nervous system (CNS) infection remains elusive. HIV is not only able to establish a viral reservoir in the CNS but also to initiate manifestation of neurodegenerative di...

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Detalles Bibliográficos
Autores principales: Ojeda, Diego S., Grasso, Daniel, Urquiza, Javier, Till, Andreas, Vaccaro, María Inés, Quarleri, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255949/
https://www.ncbi.nlm.nih.gov/pubmed/30515154
http://dx.doi.org/10.3389/fimmu.2018.02633