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Additional evidence for a therapeutic effect of dextromethorphan/quinidine on bulbar motor function in patients with amyotrophic lateral sclerosis: A quantitative speech analysis

AIMS: A recent double‐blind placebo‐controlled crossover 70‐day trial demonstrated that a fixed combination of dextromethorphan and quinidine (DM/Q) improves speech and swallowing function in most patients with amyotrophic lateral sclerosis. In this study, a subset of participants, many of whom did...

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Detalles Bibliográficos
Autores principales: Green, Jordan R., Allison, Kristen M., Cordella, Claire, Richburg, Brian D., Pattee, Gary L., Berry, James D., Macklin, Eric A., Pioro, Erik P., Smith, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256051/
https://www.ncbi.nlm.nih.gov/pubmed/30152872
http://dx.doi.org/10.1111/bcp.13745