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Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

[Image: see text] Mass spectrometry imaging (MSI) has proven to be a valuable tool for drug and metabolite imaging in pharmaceutical toxicology studies and can reveal, for example, accumulation of drug candidates in early drug development. However, the lack of sample cleanup and chromatographic sepa...

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Detalles Bibliográficos
Autores principales: Lamont, Lieke, Eijkel, Gert B., Jones, Emrys A., Flinders, Bryn, Ellis, Shane R., Porta Siegel, Tiffany, Heeren, Ron M.A., Vreeken, Rob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256344/
https://www.ncbi.nlm.nih.gov/pubmed/30346139
http://dx.doi.org/10.1021/acs.analchem.8b03857