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Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry
[Image: see text] Mass spectrometry imaging (MSI) has proven to be a valuable tool for drug and metabolite imaging in pharmaceutical toxicology studies and can reveal, for example, accumulation of drug candidates in early drug development. However, the lack of sample cleanup and chromatographic sepa...
Autores principales: | Lamont, Lieke, Eijkel, Gert B., Jones, Emrys A., Flinders, Bryn, Ellis, Shane R., Porta Siegel, Tiffany, Heeren, Ron M.A., Vreeken, Rob J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256344/ https://www.ncbi.nlm.nih.gov/pubmed/30346139 http://dx.doi.org/10.1021/acs.analchem.8b03857 |
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